Preterm birth poses a threat to the life and health of the unborn child. Most early neonatal (70%) and childhood (65-75%) deaths occur in premature babies. Stillbirth in preterm birth is 9-13 times higher than in urgent. In surviving children, complications are registered ten times more often than in full-term ones: blindness, deafness, cerebral palsy, mental disorders and chronic pulmonary pathologies. For the mother, a particular danger is incomplete abortion, non-developing pregnancy, the complications of which are bleeding, infection of the uterus and membranes, DIC.